Main Sector of relevance\IRC classification 10. Other Industrial Manufacturing Technologies


10.11 FLUDARABEL – pharmaceutical substance and medical drug

FLUDARABEL

Developers’ contact information

State Scientific Institution “The Institute of Bioorganic Chemistry of the National Academy of Sciences of Belarus”
5, bldg. 2, Kuprevich Str., 220141 Minsk

E.N. Kalinichenko
tel/fax: +375 (17) 267-87-61; e-mail: babitskaya@iboch.bas-net.by

Summary

FLUDARABEL is one of the most effective and perspective medical drugs for treatment of chronic B-cell lymphocytic leukaemia

Description

The original technology of chemosynthesis of the substance is protected by patent for invention of the Republic of Belarus No. 9975

Technology type

Technical advantages and economic benefits

FLUDARABEL is one of the most effective and perspective medical drugs for treatment of chronic B-cell lymphocytic leukaemia. The original and extremely effective technology makes it possible to obtain a substance of pharmacopeial purity (more than 99.6%) with high yield and freeze dried pharmaceutical form containing 0.5g of active substance. The developed technology allows reducing the drug price 1.5-fold in comparison to the analogue foreign drugs. FLUDARABEL is not produced on the territory of CIS countries.

Technology differentiation and uniqueness

The original high-technology synthesis scheme.

Context in which technology was identified

International Specialized Exhibition “Chemistry. Oil and Gas” 2006, 2008; National exhibition of the Republic of Belarus in the Bolivarian Republic of Venezuela “Expo Feria “BELARUS-2007”

Technological keywords

Anticancer drug, chronic lymphocytic leukaemia.

Development Stage

Intellectual property rights

Range of applications

Classifier Used at the EU Innovation Relay Centres

Preferable Regions

Practical experience

Introduction of the technology in production.

Environmental impact

None

Type of collaboration sought

Terms and restrictions

Terms of the license contract

Available technical assistance