Main Sector of relevance\IRC classification 3. Biological Sciences
3.18 Oligonucleotides (primers of polymerase chain reaction)
Developers’ contact information
State Scientific Institution “The Institute of Physical Organic Chemistry of the National Academy of Sciences of Belarus”
13, Surganov Str., 220072 Minsk
Summary
Biomolecular analysis is one of the most advanced and fast-developing scientific-practical tendencies in the world. Its practical worth consists in use of special links, short fragments of DNA molecules (oligonucleotides), produced as a result of chemical synthesis. These fragments present the main component of diagnostic analytical systems, based on polymerase chain reaction (PCR). The aim of the study is to develop the technology and to master the production of knowledge-intensive chemical products – oligonucleids that are used for PCR and molecular biology, genetic analysis and genetic engineering. Introduction of the technology will fully cover the need of the Republic in oligonucleids both for scientific research purposes and for clinical diagnostics with the perspective of exporting the product in the future.
Description
Oligonucleids (short DNA fragments) are essential for polymerase chain reaction (PCR), lying in the basis of determining the necessary sequences of DNA in genetic analysis and biomolecular studies.
Technology type
Technical advantages and economic benefits
The quality of product corresponds to the analogue oligonucleids produced in Russia and Europe. The calculated price is much lower than that of the foreign analogues.
Technology differentiation and uniqueness
Creation of scientifically intensive production that is in demand among Belarusian and foreign customers.
Context in which technology was identified
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Technological keywords
PCR, polymerase chain reaction, primers, oligonucleid synthesis, DNA
Development Stage
Intellectual property rights
Range of applications
To perform PCR – the most modern and informative method of genetic analysis – short DNA fragments are need (oligonucleotides, PCR primers). They are produced by means of chemical synthesis and are further used in scientific researches and clinical diagnostics as a part of PCR kits that help to determine a number of human and animal infections (clamidiosis, tuberculoses, bird flu), genetic diseases, genetic relationship, genetically modified products, etc.
Classifier Used at the EU Innovation Relay Centres
Preferable Regions
Practical experience
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Environmental impact
None
Type of collaboration sought
Terms and restrictions
— None
Available technical assistance