Main Sector of relevance\IRC classification 1. Agriculture, Food and Marine Resources
1.61 Recombinant thermostable DNA polymerase (Taq and Pfu)
Developers’ contact information
State Scientific Institution “The Institute of Bioorganic Chemistry of the National Academy of Sciences of Belarus”
220141, Minsk, Kuprevich St., 5/2
Tel./Fax:+375 (17) 267-87-61
Summary
Recombinant thermostable DNA polymerase (Taq and Pfu) is the main component of the polymerase chain reaction.
Description
The discovery of thermostable DNA-polymerase has revolutionized molecular biology and contributed to the creation of the method of polymerase chain reaction. Currently it is the most sensitive and up-to-date method for detection of foreign DNA in human, animals and plants which serves to create highly sensitive systems of genetic diagnostics such as direct detection and identification of infectious agents, molecular genotyping and studies of the properties of pathogenic microorganisms, analysis of the mutations connected with human genetic diseases, identification of personality. Recombinant thermostable DNA polymerase can be used as separate products as well as parts of PCR sets of different orientation.
Technology type
Technical advantages and economic benefits
Domestic manufacturing of thermostable DNA polymerase makes it possible to reduce the price of one thousand units of enzyme by 50% from the price of similar products of Fermentas or NEB companies.
Technology differentiation and uniqueness
New technology.
Context in which technology was identified
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Technological keywords
PCR, thermostable DNA polymerase.
Development Stage
Intellectual property rights
Range of applications
Medical clinical diagnostics, veterinary diagnostics, legal expertise.
Classifier Used at the EU Innovation Relay Centres
Preferable Regions
Practical experience
The technology is introduced and implemented.
Environmental impact
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Type of collaboration sought
Terms and restrictions
License contract terms.
Support provided at transfer of the technology