Main Sector of relevance\IRC classification 1. Agriculture, Food and Marine Resources
1.53 Develop new domestic products and integrated ways to deal with Philometroides fish infection and introduce them into production
Developers’ contact information
Republican Subsidiary Unitary Enterprise “The Institute
for Fish Industry” of Republican Unitary Enterprise “The Scientific and
Practical Center for Animal Breeding”
220024, Minsk, Stebenev St., 22
Теl.+375 (17) 275-16-25, Fax +375 (17) 275-30-60
Summary
A drug for anthelminthic treatment of pond fish (carp, European carp and their hybrids, crucian carp) with Philometroides lusiana infection. Antihelminthic against nematode infection.
Description
Timtetrazole (Timtetrazolum), (tetramizole, nilverm) (D,
L - 2-3-5-6-tetrahydro-6-phenyl-imidazo-(2,1-B)-thiazole-hydrochloride
- granular antihelmintic of nematode action spectrum containing 20% of
the active substance (ADV) tetramizole hydrochloride and bulking agents
(lactose, cattle chalk, precipitated chalk, or other inert materials).
The
drug consists of white granules with faint characteristic smell. It is
well disintegrated in the wet feed. Timtetrazole is stable during three
years storage (factory packaging, dark, dry place at temperatures from
+4 to +25 ° C).
Active substance - tetramizole hydrochloride –
disturbs the nematode energy metabolism and inhibits the synthesis of
adenosine triphosphate acid, inhibits the activity of fumarate and
succinate dehydrogenase.
Timtetrazole is a low-toxic
anthelminthic, it is well absorbed from the gastrointestinal tract,
does not have teratogenic, embryotoxic and allergenic properties.
Timtetrazole
is used as therapeutic pellets at a dose of 15 mg ADV / kg of fish (4kg
of timtetrazole per 1 ton of combined feed).
Therapeutic pellets
with timtetrazole are used at a rate of 5% from weight of fish by the
method group feeding during two consecutive days. Preimaginal
anthelminthic treatment is conducted in the summer (III ten-day period
of July - I ten-day period of August) with water temperature no less
than 16-18 ° C. Side effects of applying timtetrazole in such doses in
pond fish were not found.
Technology type
Technical advantages and economic benefits
Domestic therapeutic drug, more effective and cheaper than imported analogs. Implementation of this development will increase the fish productivity up to 10%, lower the cost of antiepizootic measures up to 30-40% of, to save currency fund, and also export products.
Technology differentiation and uniqueness
Modern domestic drug effective in treatment against nematodoses.
Context in which technology was identified
The drug is introduced and widely used in fish farms of the Republic of Belarus and the near broad countries and abroad.
Technological keywords
Nematodoses, Philometroides infection, anthelminthic, prevention, treatment, timtetrazole-20.
Development Stage
Intellectual property rights
Range of applications
Fish farming, veterinary science.
Classifier Used at the EU Innovation Relay Centres
Preferable Regions
Practical experience
The drug is introduced and applied.
Environmental impact
—
Type of collaboration sought
Terms and restrictions
—
Support provided at transfer of the technology