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Increasing the biomolecules fluorescence intensity
Link to Contact Information (Only For Members of GetOwner Role)
Ref: TO
2256
Submission Date:
12/02/2019
Active before:
31/12/2021
Contact Information
Department:
The Department of Physics, Mathematics and Informatics
Organization:
The State Scientific Institution "The B.I. Stepanov Institute of Physics of the National Academy of Sciences of Belarus"
Name:
Jarnikova Ekaterina
Email:
ifanbel@ifanbel.bas-net.by
Telephone:
+375172841750
Link to website:
[url]http://ifanbel.bas-net.by/[/url]
Link to the corresponding profile in Russian
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Description
The technique for multilayer nanostructure synthesis is developed, which allows increasing the fluorescence intensity of the labeled biomolecules adsorbed on their surface up to 10 times. The technique does not contain costly processes of nanolithography and vacuum deposition.[br][/br]The physical processes, which determine the increase in fluorescence intensity, are plasmon effects leading to the local concentration of electromagnetic radiation and possible increase in quantum transitions. The technique is realized for the model structures, such as[br][/br]bovine serum albumin and immunoglobulin labeled with fluorescein, and can be used to increase the detection sensitivity of cancer markers by immunofluorescent analysis
Technology Differentiation and Uniqueness
new technologies
Technological Keywords
The physical processes, fluorescence intensity, plasmon effects, l local concentration, electromagnetic radiation, quantum transitions. albumi, immunoglobulin, fluorescein, detection sensitivity, cancer markers, immunofluorescent analysis
Development Stage
Results of demonstration test available
Currently in use/production
Intellectual Property Rights
Secret Know-How
Range of Applications
medicine, immunofluorescent analysis
Classifier Used at the Enterprise Europe Network
Biotech, Pharma and Cosmetics
Environment
Healthcare
Materials
Classifier Used at the Technology Transfer Network of yet2.com Inc.
Biological Sciences
Health, Wellness, Personal Care
Optics
Physics
Preferable Regions
North America
South America
Europe
Asia
Africa
Australia
Environmental Impact
no
Type of Collaboration Sought
R&D Contract
License
For Sale
Terms&Restrictions
no
Available Technical Assistance
Documentation
Personnel
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